Another Testosterone Booster? Think Again!
A lot of “testosterone boosters” seem to make crazy claims like “BOOST TESTOSTERONE BY 1200%!” — or by some unbelievable crazy amount. The truth is, most of these claims are the result of unnatural steroids in the product, or flat out lies.
Human research shows that supplementing with DAA can increase total testosterone production by 42% in only 12 days. (1)
Out of the 23 participants in the human trial, 20 had a significant increase in testosterone after just 12 days. The placebo group did not have an increase in testosterone. (1)
A 42% increase in total testosterone after 12 days is nothing short of phenomenal. What makes DAA so compelling is that these results were accomplished by a single naturally occurring D-amino acid and only this specific D-amino acid has this testosterone boosting ability. (1-3)
DAA A Critical Factor for Male Health
Boosting total testosterone by 42% will have some serious physical and mental benefits, but personally I’m more excited about how DAA works, than the benefits it provides.
As far as we know, DAA is the only bio-available, naturally occurring amino acid shown to have such a profound effect on total testosterone levels in healthy men. (1-3) As you can see from the graph above DAA is a powerful LH booster, but it’s not the primary mechanism of how DAA increases testosterone it’s something else, something much more interesting.
DAA directly up-regulates the most important factor in testosterone creation cholesterol transfer. (3-4)
In the following segments you will learn exactly why this is so important and why it’s a must have supplement for any man seeking to naturally increase his testosterone levels.
The Testosterone Production Line
When testosterone levels are low, the brain senses this, and pulses a large dose of luteinizing hormone (LH) into the blood stream.
The cells in the testes responsible for creating testosterone are called leydig cells. So, the LH travels to the leydig cells and transmits a message to “increase testosterone production”.
Once LH binds to the outside of the cell it begins communicating the message to “increase testosterone” by sending out commands to the cellular hormone stations within the cell such as the powerhouse of the cell, the mitochondria which is responsible for the first step in hormone production. (3-4)
Since cholesterol is the starting material for all hormones, the mitochondria is ordered to collect nearby cholesterol. Because cholesterol cannot pass the walls of the mitochondria on its own, a special transport protein is produced to wrap around cholesterol and carry it through the walls of the mitochondria. This is a very important job which is specifically assigned to steroidogenic acute regulatory protein (sTAR). (3-4)
And here we reach the bottleneck:
sTAR – The Bottleneck of Testosterone
Getting cholesterol inside the mitochondria is the rate limiting step of testosterone production and sTAR is the key transporter in this process. (2-4)
I’ll say it again, because it’s so important:
The transport of cholesterol into the mitochondria via sTAR is the rate-limiting step — the critical control point the slow point in testosterone creation.
Therefore, no matter how much LH or cholesterol you have in your body, testosterone production will always be limited by the amount of cholesterol that can be brought into the mitochondria via sTAR. Increasing sTAR should be the #1 priority for any male trying to increase his testosterone level.
DAA Increases Mitochondrial sTAR by 90%
Incubation of testicular cells with DAA has shown to directly increase sTAR protein levels by 90% within the mitochondria. Researchers propose this is a result of DAA enhancing sTAR mRNA levels, thus enhancing replication of the sTAR protein. (4)
This is the primary mechanism that makes DAA so special. DAA is one of the only amino acids known to significantly increase the level of cholesterol transport protein (sTAR) within the mitochondria. (1-4)
The process of DAA, sTAR and testosterone conversion looks like this:
- DAA increases production of sTAR in the cell mitochondria.
- sTAR pulls cholesterol into the mitochondria of the cell.
- Once in the mitochondria, cholesterol begins converting into testosterone.
With higher amounts of sTAR in the mitochondria, more cholesterol will be transported into the mitochondria for processing into testosterone. This will increase the testosterone production in response to stimulus. (3-5)
In other words, by increasing sTAR, DAA will result in
- Higher testosterone output from the body’s natural LH stimulus (1, 3, 6)
- Higher testosterone output from exogenous hCG stimulus (3)
Yes, you read that right. DAA enhances testosterone output from the testes in response to LH or hCG by increasing the testes ability to turn cholesterol into testosterone. In addition, DAA is also a powerful LH booster. (1,6)
This makes DAA an essential supplement for men who
- Have low LH and low testosterone and want to restore normal levels of both
- Have normal LH with low testosterone and want to restore testosterone levels
- Have normal LH and testosterone and want to increase production of both
Post Cycle Therapy? You bet
Right about now you are probably realizing that DAA is a must have for post cycle therapy (PCT). It’s true, DAA can dramatically improve recovery of natural T levels and would have synergistic effects with Res100.
Store in a dry cool place away from light.
All 3 products can be stacked together to have a synergistic effect to further enhance testosterone levels.
1. The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats. Antimo D’Aniello et al. Reproductive Biology and Endocrinology 2009, 7;120
2. D-Aspartic acid: An endogenous amino acid with an important neuroendocrine role. Antimo D’ Anello Brain Research Reviews 53;215-234 (2007)
3. D-Aspartate stimulation of testosterone synthesis in rat Leydig cells. FEBS Nagata, Y., et al. Lett. 444, 160–164. (1999)
4. Stimulation of steroidogenic acute regulatory protein (stAR) gene expression by D-aspartate in rat Leydig cells. Nagata, Y., et al. FEBS Lett. 454, 317–320. (1999)
5. Regulation of Leydig Cell Steroidogenic Function During Aging Barry R. et al. BIOLOGY OF REPRODUCTION 63, 977–981 (2000)
6. Involvement of D-aspartic acid in the synthesis of testosterone in rat testes. D’Aniello, A., et al. Life Sci. 59, 97–104. (1996)
Frequently Asked Questions
D-AA can upset my stomach what can i do to reduce this?
Regular D-AA can give you an upset stomach to reduce this you should take the D-AA with a meal, should you still have further issues you can take TransSynergy DAA it is similar to this product however it absorbs much better and has several other features.